Dandanes, za farmacevtske izdelke in kozmetiko, je domači trg preplavljen z različnimi farmacevtskimi pomožniki. Na splošno, čeprav so učinki podobni, so učinki mešani in seveda je na različnih področjih preučiti veliko vsebin. Številne kozmetike in farmacevtske sestavine doma in v tujini vsebujejo hidroksipropil beta-ciklodekstrin, zato kratek uvod v ta farmacevtski pomočniki-hidroksipropil beta-ciklodektrin.
Hidroksipropil betaciklodekstrinje hidrofilni derivat betaciklodekstrina, kondenziranega z 1, 2- propilen oksid. The hydroxyl groups at positions 2, 3 and 6 on cyclodextrin may be modified by hydroxypropyl groups to hydroxypropoxy groups, so that the molecular structure of hydroxypropyl betacyclodextrin contains a hydrophilic outer surface and a hydrophobic pores, which allow cyclodextrin to embed the guest molecule and form an inclusion kompleksno, s čimer igra vlogo pri solubilizaciji in stabilizaciji zdravila. At present, hydroxypropyl betacyclodextrin has been included in the fourth part of the 2015 edition of the Chinese Pharmacopoeia and the 8.0 edition of the European Pharmacopoeia, which stipulates that it can be used for intravenous preparations, and the US FDA also approved it as an excipient in itraconazole injection as early as 1999. Because the adverse reactions of Intravenski hidroksipropil betaciklodekstrin se manifestira predvsem v nefrotoksičnosti in hemolizi, še vedno obstajajo pomisleki glede njene varnosti za intravensko dajanje na Kitajskem.
